TY - JOUR
T1 - Significance of nocturia in the international prostate symptom score for benign prostatic hyperplasia
AU - Homma, Yukio
AU - Yamaguchi, Takuhiro
AU - Kondo, Yasushi
AU - Horie, Shigeo
AU - Takahashi, Sarotu
AU - Kitamura, Tadaichi
PY - 2002
Y1 - 2002
N2 - Purpose: We studied the relationship of nocturia with the International Prostate Symptom Score in men with lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). Materials and Methods: Baseline symptom score and the change in the score by treatment were analyzed in 219 consecutive Japanese men with BPH using basic statistics, and correlation, cluster and principal component analyses. Results: The average nocturia score was the middle of that of the 7 symptoms at baseline and by far the highest aider treatment. Hence, the score change was the smallest. Analysis of baseline scores demonstrated that all symptoms were the initial component in principal component analysis with individual symptom scores correlating with the total symptom score and quality of life index. However, the correlation was least for nocturia. Observations were similar when analyzing the score change by treatment. These results indicate that the nocturia score is least specific to symptoms associated with BPH or least sensitive to the therapeutic effect on symptoms. This finding may be related to the high nocturia score in the age matched control population. Conclusions: The nocturia score of the International Prostate Symptom Score behaves differently in the symptom complex of BPH in Japanese men, partially because it is most confounded by the aging factor.
AB - Purpose: We studied the relationship of nocturia with the International Prostate Symptom Score in men with lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). Materials and Methods: Baseline symptom score and the change in the score by treatment were analyzed in 219 consecutive Japanese men with BPH using basic statistics, and correlation, cluster and principal component analyses. Results: The average nocturia score was the middle of that of the 7 symptoms at baseline and by far the highest aider treatment. Hence, the score change was the smallest. Analysis of baseline scores demonstrated that all symptoms were the initial component in principal component analysis with individual symptom scores correlating with the total symptom score and quality of life index. However, the correlation was least for nocturia. Observations were similar when analyzing the score change by treatment. These results indicate that the nocturia score is least specific to symptoms associated with BPH or least sensitive to the therapeutic effect on symptoms. This finding may be related to the high nocturia score in the age matched control population. Conclusions: The nocturia score of the International Prostate Symptom Score behaves differently in the symptom complex of BPH in Japanese men, partially because it is most confounded by the aging factor.
KW - Prostate
KW - Prostatic hyperplasia
KW - Questionnaires
KW - Urination disorders
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U2 - 10.1016/S0022-5347(05)65406-7
DO - 10.1016/S0022-5347(05)65406-7
M3 - Article
C2 - 11743299
AN - SCOPUS:0036135219
VL - 167
SP - 172
EP - 176
JO - Investigative Urology
JF - Investigative Urology
SN - 0022-5347
IS - 1
ER -