Signal intensity changes on MRI during the healing process of spinal Langerhans cell granulomatosis: Report of two cases

Toshimi Aizawa, Tetsuro Sato, Yasuhisa Tanaka, Shoichi Kokubun

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Two patients with spinal Langerhans cell granulomatosis were followed by magnetic resonance imaging, and the observed signal changes were detailed. Both patients had no neurologic abnormalities but back pain. They were treated by immobilization with a brace and bed rest. Their back pain disappeared after about a month. At the first visit, the tumorous lesions involving vertebrae showed mainly low signal intensity on T1-weighted imaging (T1WI) and high intensity on T2-weighted imaging (T2WI). They were clearly enhanced by gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA). Their original intensities changed to iso-intensities on both T1WI and T2WI without enhancement by Gd-DTPA after a year. These signal changes might indicate the healing stage of the involved vertebrae and recommend the removal of the spinal brace.

Original languageEnglish
Pages (from-to)98-101
Number of pages4
JournalJournal of Spinal Disorders and Techniques
Volume18
Issue number1
DOIs
Publication statusPublished - 2005 Feb
Externally publishedYes

Keywords

  • Eosinophilic granuloma
  • Langerhans cell granulomatosis
  • Magnetic resonance imaging
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology

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