Abstract
Three sialyl oligosaccharide fractions were separated from ovine colostrum by gel filtration, anion exchange chromatography and normal-phase HPLC. They were characterized by 1H-NMR spectrometry as follows: Neu5Acα2→3Galβ1→4Glc, Neu5Gcα2→6Galβ1→4Glc and three forms of Neu5Gcα2→3Galβ1→4Glc, namely Neu5Gcα2→3Galβ1→4Glc itself, its lactone derivative between the carboxyl group of Neu5Gc and Gal OH-2 and another lactone derivative between the carboxyl group and Gal OH-4. In this study, Neu5Gc-lactose lactones, in their free form, have been isolated for the first time from any natural sources including milk or colostrum. Copyright (C) 1998 Elsevier Science B.V.
| Original language | English |
|---|---|
| Pages (from-to) | 286-292 |
| Number of pages | 7 |
| Journal | Biochimica et Biophysica Acta - General Subjects |
| Volume | 1381 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1998 Aug 24 |
Keywords
- Colostrum
- Lactone
- Ovine
- Sialyllactose
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
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Cite this
Nakamura, T., Urashima, T., Nakagawa, M., & Saito, T. (1998). Sialyllactose occurs as free lactones in ovine colostrum. Biochimica et Biophysica Acta - General Subjects, 1381(3), 286-292. https://doi.org/10.1016/S0304-4165(98)00040-3