Short-term topical therapy of experimental tinea pedis in guinea pigs with lanoconazole, a new imidazole antimycotic agent

Y. Niwano, T. Tabuchi, K. Kanai, H. Hamaguchi, K. Uchida, H. Yamaguchi

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

The therapeutic efficacy of short-term treatment with a 1% cream of lanoconazole, a new imidazole antimycotic agent, in comparison with that of a 1% cream of terbinafine was evaluated in the guinea pig model of tinea pedis. Each agent was topically applied once a day for 3 or 7 consecutive days, starting on day 10 postinfection, and a culture study was conducted on day 5 after the last treatment with each agent. The 1% cream of lanoconazole was as highly effective as the 1% cream of terbinafine in terms of eradicating the fungi from the infected feet.

Original languageEnglish
Pages (from-to)2353-2355
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume39
Issue number10
DOIs
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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