Shoot control of root development and nodulation is mediated by a receptor-like kinase

Lene Krusell, Lene H. Madsen, Shusei Sato, Grégoire Aubert, Aratz Genua, Krzysztof Szczyglowski, Gérard Duc, Takakazu Kaneko, Satoshi Tabata, Frans De Bruijn, Eloisa Pajuelo, Niels Sandal, Jens Stougaard

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390 Citations (Scopus)

Abstract

In legumes, root nodule organogenesis is activated in response to morphogenic lipochitin oligosaccharides that are synthesized by bacteria, commonly known as rhizobia. Successful symbiotic interaction results in the formation of highly specialized organs called root nodules, which provide a unique environment for symbiotic nitrogen fixation. In wild-type plants the number of nodules is regulated by a signalling mechanism integrating environmental and developmental cues to arrest most rhizobial infections within the susceptible zone of the root. Furthermore, a feedback mechanism controls the temporal and spatial susceptibility to infection of the root system. This mechanism is referred to as autoregulation of nodulation, as earlier nodulation events inhibit nodulation of younger root tissues. Lotus japonicus plants homozygous for a mutation in the hypernodulation aberrant root (harl) locus escape this regulation and form an excessive number of nodules. Here we report the molecular cloning and expression analysis of the HAR1 gene and the pea orthologue, Pisum sativum, SYM29. HAR1 encodes a putative serine/threonine receptor kinase, which is required for shoot-controlled regulation of root growth, nodule number, and for nitrate sensitivity of symbiotic development.

Original languageEnglish
Pages (from-to)422-426
Number of pages5
JournalNature
Volume420
Issue number6914
DOIs
Publication statusPublished - 2002 Nov 28
Externally publishedYes

ASJC Scopus subject areas

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    Krusell, L., Madsen, L. H., Sato, S., Aubert, G., Genua, A., Szczyglowski, K., Duc, G., Kaneko, T., Tabata, S., De Bruijn, F., Pajuelo, E., Sandal, N., & Stougaard, J. (2002). Shoot control of root development and nodulation is mediated by a receptor-like kinase. Nature, 420(6914), 422-426. https://doi.org/10.1038/nature01207