TY - JOUR
T1 - Severity of eczema and mental health problems in Japanese schoolchildren
T2 - The ToMMo Child Health Study
AU - Kuniyoshi, Yasutaka
AU - Kikuya, Masahiro
AU - Miyashita, Masako
AU - Yamanaka, Chizuru
AU - Ishikuro, Mami
AU - Obara, Taku
AU - Metoki, Hirohito
AU - Nakaya, Naoki
AU - Nagami, Fuji
AU - Tomita, Hiroaki
AU - Hozawa, Atsushi
AU - Tsuji, Ichiro
AU - Kure, Shigeo
AU - Yaegashi, Nobuo
AU - Yamamoto, Masayuki
AU - Kuriyama, Shinichi
N1 - Funding Information:
This work was supported by the MEXT Tohoku Medical Megabank Project and Japan Agency for Medical Research and Development (AMED) under Grant Number JP15km0105001 . We would like to thank the Miyagi Prefectural Board of Education and the municipal boards of education in Shiroishi, Natori, Kakuda, Zao, Shichikashuku, Ogawara, Murata, Shibata, Kawasaki, Marumori, Kesennuma, Tome, Kurihara, Higashimatsushima, Osaki, Shichigahama, Taiwa, Osato, Ohira, Shikama, Kami, Wakuya, Misato, Onagawa, and Minamisanriku for participating in the study.
Funding Information:
This work was supported by the MEXT Tohoku Medical Megabank Project and Japan Agency for Medical Research and Development (AMED) under Grant Number JP15km0105001. We would like to thank the Miyagi Prefectural Board of Education and the municipal boards of education in Shiroishi, Natori, Kakuda, Zao, Shichikashuku, Ogawara, Murata, Shibata, Kawasaki, Marumori, Kesennuma, Tome, Kurihara, Higashimatsushima, Osaki, Shichigahama, Taiwa, Osato, Ohira, Shikama, Kami, Wakuya, Misato, Onagawa, and Minamisanriku for participating in the study.
Publisher Copyright:
© 2018 Japanese Society of Allergology
PY - 2018/10
Y1 - 2018/10
N2 - Background: The association between eczema and mental health problems in schoolchildren has been underexplored. We aimed to investigate this association with the validated questionnaires. Methods: Of 46,648 invited children, we analyzed 9954 (21.3%) in the 2nd to the 8th grades from the ToMMo Child Health Study conducted in 2014 and 2015, a cross-sectional survey in Miyagi Prefecture, Japan. We defined eczema status as “normal,” “mild/moderate,” or “severe,” based on the presence of persistent flexural eczema and sleep disturbance, according to the International Study of Asthma and Allergies in Childhood (ISAAC) Eczema Symptom Questionnaire. Clinical ranges of Strengths and Difficulties Questionnaire (SDQ) total difficulties scores and four SDQ subcategories of emotional symptoms, conduct problems, hyperactivity/inattention, and peer problems were defined as scores ≥16, ≥5, ≥5, ≥7, and ≥5, respectively. Results: The mean SDQ total difficulties score significantly increased as eczema status worsened (all P ≤ 0.004 for trend). The OR of scores in the clinical range for SDQ total difficulties were 1.51 (95% CI, 1.31–1.74) for mild/moderate eczema and 2.63 (95% CI, 1.91–3.63) for severe eczema (P < 0.001 for trend), adjusted for sex, school grade, current wheeze, and disaster-related factors, using normal eczema as a reference. The association between severity of eczema and four SDQ subcategories showed a similar trend (all P ≤ 0.017 for trend). Conclusions: We found a significant association between severity of eczema and mental health problems. The presence of eczema was associated with four SDQ subcategories.
AB - Background: The association between eczema and mental health problems in schoolchildren has been underexplored. We aimed to investigate this association with the validated questionnaires. Methods: Of 46,648 invited children, we analyzed 9954 (21.3%) in the 2nd to the 8th grades from the ToMMo Child Health Study conducted in 2014 and 2015, a cross-sectional survey in Miyagi Prefecture, Japan. We defined eczema status as “normal,” “mild/moderate,” or “severe,” based on the presence of persistent flexural eczema and sleep disturbance, according to the International Study of Asthma and Allergies in Childhood (ISAAC) Eczema Symptom Questionnaire. Clinical ranges of Strengths and Difficulties Questionnaire (SDQ) total difficulties scores and four SDQ subcategories of emotional symptoms, conduct problems, hyperactivity/inattention, and peer problems were defined as scores ≥16, ≥5, ≥5, ≥7, and ≥5, respectively. Results: The mean SDQ total difficulties score significantly increased as eczema status worsened (all P ≤ 0.004 for trend). The OR of scores in the clinical range for SDQ total difficulties were 1.51 (95% CI, 1.31–1.74) for mild/moderate eczema and 2.63 (95% CI, 1.91–3.63) for severe eczema (P < 0.001 for trend), adjusted for sex, school grade, current wheeze, and disaster-related factors, using normal eczema as a reference. The association between severity of eczema and four SDQ subcategories showed a similar trend (all P ≤ 0.017 for trend). Conclusions: We found a significant association between severity of eczema and mental health problems. The presence of eczema was associated with four SDQ subcategories.
KW - Atopic dermatitis
KW - Cross-sectional survey
KW - ISAAC
KW - Sleep disorders
KW - Strengths and difficulties questionnaire
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U2 - 10.1016/j.alit.2018.02.009
DO - 10.1016/j.alit.2018.02.009
M3 - Article
C2 - 29661500
AN - SCOPUS:85045323225
VL - 67
SP - 481
EP - 486
JO - Allergology International
JF - Allergology International
SN - 1323-8930
IS - 4
ER -
