Abstract
To elucidate the cause of growth retardation, 14 cattle with renal tubular dysplasia (RTD) were investigated by determining serum growth hormone (GH) and insulin-like growth factor (IGF)-1 concentrations. Compared with 6 healthy cattle, the baseline, maximum, area under the curve and peak amplitude of serum GH concentrations were higher or tended to be higher. Serum IGF-1 concentrations were lower normal or lower in cattle with RTD than in healthy cattle. Serum IGF-1 concentrations correlated significantly with body weight and chest girth, but not with serum GH and creatinine concentrations. Growth retardation in RTD might be associated partially with GH resistance.
Original language | English |
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Pages (from-to) | 399-402 |
Number of pages | 4 |
Journal | Journal of Veterinary Medical Science |
Volume | 67 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2005 Apr |
Keywords
- Growth hormone
- Growth retardation
- IGF-1
- Japanese black cattle
- Renal tubular dysplasia
ASJC Scopus subject areas
- veterinary(all)