Serum growth hormone and insulin-like growth factor-1 concentrations in Japanese black cattle with renal tubular dysplasia

Naohito Nishii, Yasunori Ohba, Masaki Takasu, Kazuo Katoh, Katsuya Kitoh, Yoshihide Sasaki, Hitoshi Kitagawa

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)

    Abstract

    To elucidate the cause of growth retardation, 14 cattle with renal tubular dysplasia (RTD) were investigated by determining serum growth hormone (GH) and insulin-like growth factor (IGF)-1 concentrations. Compared with 6 healthy cattle, the baseline, maximum, area under the curve and peak amplitude of serum GH concentrations were higher or tended to be higher. Serum IGF-1 concentrations were lower normal or lower in cattle with RTD than in healthy cattle. Serum IGF-1 concentrations correlated significantly with body weight and chest girth, but not with serum GH and creatinine concentrations. Growth retardation in RTD might be associated partially with GH resistance.

    Original languageEnglish
    Pages (from-to)399-402
    Number of pages4
    JournalJournal of Veterinary Medical Science
    Volume67
    Issue number4
    DOIs
    Publication statusPublished - 2005 Apr

    Keywords

    • Growth hormone
    • Growth retardation
    • IGF-1
    • Japanese black cattle
    • Renal tubular dysplasia

    ASJC Scopus subject areas

    • veterinary(all)

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