Serotypes VI and VIII predominate among group B streptococci isolated from pregnant Japanese women

Catherine S. Lachenauer, D. L. Kasper, J. Shimada, Y. Ichiman, H. Ohtsuka, M. Kaku, L. C. Paoletti, P. Ferrieri, L. C. Madoff

Research output: Contribution to journalArticlepeer-review

142 Citations (Scopus)

Abstract

Infection by group B streptococcus (GBS) is an important cause of bacterial disease in neonates, pregnant women, and nonpregnant adults. Whereas serotypes Ia, Ib, II, III, and V are most commonly associated with colonization and disease in the United States, strains of other serotypes have been isolated from patients in Japan. By use of an inhibition ELISA, the serotypes of 73 vaginal colonizing GBS strains isolated from healthy pregnant Japanese women were investigated. Twenty-six (35.6%) were type VIII, 18 (24.7%) were type VI, and the remaining 29 were distributed among more traditional serotypes. Strains were also tested by immunoblot for the presence of GBS surface proteins. Fifty-three (72.6%) of the 73 strains expressed one or more laddering GBS proteins. These data show that type VI and VIII GBS strains are common vaginal isolates in pregnant Japanese women and that one or more laddering proteins are present in most GBS strains.

Original languageEnglish
Pages (from-to)1030-1033
Number of pages4
JournalJournal of Infectious Diseases
Volume179
Issue number4
DOIs
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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