Abstract
The functional material micropatterns-assembled hydrogel sheet has been prepared by means of sequential transfer technique to construct the skeletal muscle cell-based assay system. We demonstrated to construct micropatterned synaptic connection between motor neurons-skeletal muscle cells using this technique. Besides, assembly of the non-biological functional materials has also advantage to confer additional functions to a hydrogel assay system. The fluorescent microbeads were assembled onto a hydrogel as sensing elements of contractile force and metabolic activity of skeletal muscle cells. These flexible sensor sheets would be useful to study the relationship between exercise and metabolic activity of muscle in type 2 diabetes.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1054-1056 |
| Number of pages | 3 |
| ISBN (Print) | 9780979806452 |
| Publication status | Published - 2012 Jan 1 |
| Event | 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan Duration: 2012 Oct 28 → 2012 Nov 1 |
Publication series
| Name | Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 |
|---|
Other
| Other | 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 |
|---|---|
| Country | Japan |
| City | Okinawa |
| Period | 12/10/28 → 12/11/1 |
Keywords
- Assembly
- Bioassay
- Hydrogel
- Skeletal muscle cell
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
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