Sepsis caused by methicillin-resistant Staphylococcus aureus (MRSA) without effects of vancomycin (VCM), teicoplanin (TEIC) and arbekacin (ABK) treated successfully and safely with intravenous administration of linezolid (LZD)

Shinya Ohkouchi, Kazunori Gomi, Yutaka Tokue, Toshiaki Kikuchi, Shigeru Fujimura, Toshihiro Nukiwa, Akira Watanabe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 77 year old man with sepsis caused by MRSA, that could not be treated by VCM, TEIC or ABK suffered severe renal failure and required immediate hemodialysis. He also suffered DIC and liver dysfunction. The administration of LZD 600 mg/day by intravenous injection ameliorated sepsis and DIC, and renal and liver function improved. LZD is thus effective in patients with sepsis caused by MRSA for whom other are ineffective drugs or who suffer severe organ dysfunction.

Original languageEnglish
Pages (from-to)787-792
Number of pages6
JournalJapanese Journal of Chemotherapy
Volume52
Issue number12
Publication statusPublished - 2004 Dec 1

Keywords

  • Linezolid
  • MRSA
  • Septicemia

ASJC Scopus subject areas

  • Pharmacology

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