TY - JOUR
T1 - Sentinel lymph node biopsy with a handheld cordless magnetic probe following preoperative MR lymphography using superparamagnetic iron oxide for clinically N0 early oral cancer
T2 - A feasibility study
AU - Sugiyama, Satomi
AU - Iwai, Toshinori
AU - Baba, Junichi
AU - Oguri, Senri
AU - Izumi, Toshiharu
AU - Kuwahata, Akihiro
AU - Sekino, Masaki
AU - Kusakabe, Moriaki
AU - Mitsudo, Kenji
N1 - Funding Information:
This research was supported by Grants-in-Aid for Scientifc Research (C) (JSPS KAKENHI Grant Numbers 15K11298 and 18K09819) from the Japan Society for the Promotion of Science, and by the Project for Medical Device Development (Grant Number JP18he0902010h0004) from Japan Agency for Medical Research and Development, Japan.
Publisher Copyright:
© 2022 Elsevier Masson SAS
PY - 2022/10
Y1 - 2022/10
N2 - Purpose: Radioisotope (RI) tracers are generally used for preoperative mapping of sentinel lymph node (SLN) and intraoperative detection with a portable γ probe. However, the use of RI has several limitations. Therefore, a method without RI is required for the widespread application of SLN biopsy. The purpose of this study was to evaluate the feasibility of SLN biopsy with a handheld cordless magnetic probe following magnetic resonance lymphography (MRL) using superparamagnetic iron oxide (SPIO) and for clinically N0 early oral cancer. Materials and methods: MRL using SPIO and SLNB with the handheld cordless magnetic probe were performed for 27 patients with clinically N0 early oral cancer. Results: In all 27 patients (100%), SLNs were detected by MRL, and the total and mean number of SLNs were 73 and 2.7, respectively. All SLNs identified by MRL were detectable using the magnetic probe in all patients. Conclusions: SLNB with handheld cordless magnetic probe following preoperative SLN mapping by MRL using SPIO is feasible, without RI use, for neck management in cases of clinically N0 early oral cancer.
AB - Purpose: Radioisotope (RI) tracers are generally used for preoperative mapping of sentinel lymph node (SLN) and intraoperative detection with a portable γ probe. However, the use of RI has several limitations. Therefore, a method without RI is required for the widespread application of SLN biopsy. The purpose of this study was to evaluate the feasibility of SLN biopsy with a handheld cordless magnetic probe following magnetic resonance lymphography (MRL) using superparamagnetic iron oxide (SPIO) and for clinically N0 early oral cancer. Materials and methods: MRL using SPIO and SLNB with the handheld cordless magnetic probe were performed for 27 patients with clinically N0 early oral cancer. Results: In all 27 patients (100%), SLNs were detected by MRL, and the total and mean number of SLNs were 73 and 2.7, respectively. All SLNs identified by MRL were detectable using the magnetic probe in all patients. Conclusions: SLNB with handheld cordless magnetic probe following preoperative SLN mapping by MRL using SPIO is feasible, without RI use, for neck management in cases of clinically N0 early oral cancer.
KW - Early oral cancer
KW - Magnetic probe
KW - Magnetic resonance lymphography
KW - Sentinel lymph node
KW - Sentinel lymph node biopsy
KW - Superparamagnetic iron oxide
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U2 - 10.1016/j.jormas.2022.01.003
DO - 10.1016/j.jormas.2022.01.003
M3 - Article
C2 - 35007780
AN - SCOPUS:85122538674
SN - 2213-6533
VL - 123
SP - 521
EP - 526
JO - Journal of Stomatology, Oral and Maxillofacial Surgery
JF - Journal of Stomatology, Oral and Maxillofacial Surgery
IS - 5
ER -
