Self-assembly of vesicle nanoarrays on Si: A potential route to high-density functional protein arrays

C. S. Ramanujan, K. Sumitomo, M. R.R. De Planque, H. Hibino, K. Torimitsu, J. F. Ryan

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

The authors show that 100 nm unilamellar thiol-tagged vesicles bind discretely and specifically to Au nanodots formed on a Si surface. An array of such dots, consisting of 20 nm Au-Si three-dimensional islands, is formed by self-assembly on terraces of small-angle-miscut Si(111) after Au deposition. Consequently, both the formation of the nanopattern and the subsequent attachment of the vesicles are self-organized and occur without the need for any "top-down" lithographic processes. This approach has the potential to provide the basis of a low-cost, high-density nanoarray for use in proteomics and drug discovery.

Original languageEnglish
Article number033901
JournalApplied Physics Letters
Volume90
Issue number3
DOIs
Publication statusPublished - 2007 Jan 29
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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