Self-assembly of synthetic glycolipid/water systems

Masakatsu Hato, Hiroyuki Minamikawa, Kaoru Tamada, Teruhiko Baba, Yoshikazu Tanabe

Research output: Contribution to journalArticlepeer-review

95 Citations (Scopus)

Abstract

Glycolipids (amphiphiles that bear oligosaccharides as their hydrophilic headgroups) are of importance both scientifically and technically. This review describes recent advances in our understanding of the molecular correlations in phase behavior in aqueous glycolipids over the past several years. In the first part, we discuss how headgroup stereochemistry affects the phase behavior of glycolipids both in two- and three-dimensional systems. In the second part, we discuss the effects of alkyl chain structure and phase behavior of phytanyl-chained glycolipid/water systems. The physical properties of glycolipid/water systems depend strongly on the inter-headgroup interactions that are related to such factors as stereochemistry (conformation) and size of headgroups, type of sugar residues involved, alkyl chain structure, etc. Thus, apart from the conventional concept like `hydrophilic/lipophilic balance', explicit accounts of headgroup interactions are crucial to control the particular glycolipid/water system concerned. This is in marked contrast to the conventional amphiphile/water systems where the inter-headgroup interactions are in most cases simply repulsive.

Original languageEnglish
Pages (from-to)233-270
Number of pages38
JournalAdvances in Colloid and Interface Science
Volume80
Issue number3
DOIs
Publication statusPublished - 1999 Apr 30
Externally publishedYes

ASJC Scopus subject areas

  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

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