Self-assembly of nanohydroxyapatite in mesoporous silica

Xuetao Shi, Yingjun Wang, Kun Wei, Li Ren, Chen Lai

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


A novel material hexagonal mesoporous silica-hydroxyapatite (HMS-HA) has been developed based on self-assembly of nanohydroxyapatite in mesoporous silica in situ. The structural and textural properties of the materials are, respectively, characterized via X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), N2 adsorption, thermogravimetic analysis, and high-resolution transmission electron spectroscopy (HRTEM). Variable crystallinity of HA involved in the mesopores yields from different sintering temperature, and correspondingly determines different degradation manners. This biocompatible new material hybridized nanoporosity to well acknowledge biofunctional scaffold (HA). It promises a high potential for application in drug and gene delivery.

Original languageEnglish
Pages (from-to)2933-2940
Number of pages8
JournalJournal of Materials Science: Materials in Medicine
Issue number8
Publication statusPublished - 2008 Aug
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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