Self-assembly of nanohydroxyapatite in mesoporous silica

Xuetao Shi, Yingjun Wang, Kun Wei, Li Ren, Chen Lai

    Research output: Contribution to journalArticlepeer-review

    28 Citations (Scopus)

    Abstract

    A novel material hexagonal mesoporous silica-hydroxyapatite (HMS-HA) has been developed based on self-assembly of nanohydroxyapatite in mesoporous silica in situ. The structural and textural properties of the materials are, respectively, characterized via X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), N2 adsorption, thermogravimetic analysis, and high-resolution transmission electron spectroscopy (HRTEM). Variable crystallinity of HA involved in the mesopores yields from different sintering temperature, and correspondingly determines different degradation manners. This biocompatible new material hybridized nanoporosity to well acknowledge biofunctional scaffold (HA). It promises a high potential for application in drug and gene delivery.

    Original languageEnglish
    Pages (from-to)2933-2940
    Number of pages8
    JournalJournal of Materials Science: Materials in Medicine
    Volume19
    Issue number8
    DOIs
    Publication statusPublished - 2008 Aug

    ASJC Scopus subject areas

    • Biophysics
    • Bioengineering
    • Biomaterials
    • Biomedical Engineering

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