Self-Assembly of M30L60 Icosidodecahedron

Daishi Fujita, Yoshihiro Ueda, Sota Sato, Hiroyuki Yokoyama, Nobuhiro Mizuno, Takashi Kumasaka, Makoto Fujita

    Research output: Contribution to journalArticlepeer-review

    140 Citations (Scopus)

    Abstract

    Self-assembly is invaluable in the construction of giant molecular structures via a bottom-up approach. Although living organisms naturally make the most use of self-assembly and freely handle the mechanism at will, scientists are still far behind the level of nature. Inspired by the elegant structures of virus capsids, we have previously constructed roughly spherical giant metal complexes with the symmetry of an octahedron, cuboctahedron, and rhombicuboctahedron with the compositions M6L12, M12L24, and M24L48, respectively. Here, we report our first successful synthesis of an M30L60 molecular icosidodecahedron that consists of ∼100 components: 30 Pd(II) ions and 60 ligands that assemble into the largest well-defined spherical macromolecule to date (diameter of ∼8.2 nm). Tuning the flexibility of the ligand was the key for successful self-assembly. A highly complex but symmetrically organized structure was identified through X-ray crystallographic analysis. The interior space of the molecular complex is large enough (157,000 Å3) to enclose proteins.

    Original languageEnglish
    Pages (from-to)91-101
    Number of pages11
    JournalChem
    Volume1
    Issue number1
    DOIs
    Publication statusPublished - 2016 Dec 1

    Keywords

    • SDG9: Industry, innovation, and infrastructure

    ASJC Scopus subject areas

    • Chemistry(all)
    • Biochemistry
    • Environmental Chemistry
    • Chemical Engineering(all)
    • Biochemistry, medical
    • Materials Chemistry

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