Self-assembled microspheres driven by dipole-dipole interactions: UCST-type transition in water

Nobuyuki Morimoto; Kanna Muramatsu; Tetsuichi Wazawa; Yuichi Inoue; Makoto Suzuki

doi:10.1002/marc.201300798

Self-assembled microspheres driven by dipole-dipole interactions: UCST-type transition in water

Nobuyuki Morimoto, Kanna Muramatsu, Tetsuichi Wazawa, Yuichi Inoue, Makoto Suzuki

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

A double hydrophilic block copolymer, poly(ethylene glycol)-poly(3-dimethyl (methacryloyloxyethyl) ammonium propane sulfonate) (PEG-SB), is synthesized by reversible addition-fragmentation transfer (RAFT) polymerization using PEG methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) as a chain transfer agent. PEG-SB forms multi-layered microspheres with dipole-dipole interactions of the SB side chains as the driving force. The PEG-SB polymers show an upper critical solution temperature (UCST) and the UCST is controllable by the polymerization degree. The PEG-SB microspheres are dissociated above the UCST and then monodispersed microspheres (∼1 μm) are obtained when the solution temperature is decreased below the UCST again. The disassociation/ association of the microspheres is also controllable using the concentration of NaCl. These multi-responsive microspheres could be a powerful tool in the field of nano-biotechnology.

Original language	English
Pages (from-to)	103-108
Number of pages	6
Journal	Macromolecular Rapid Communications
Volume	35
Issue number	1
DOIs	https://doi.org/10.1002/marc.201300798
Publication status	Published - 2014 Jan

Keywords

dipole-dipole interactions
microspheres
self-assembly
stimuli-sensitive polymers
upper critical solution temperature

ASJC Scopus subject areas

Organic Chemistry
Polymers and Plastics
Materials Chemistry

Access to Document

10.1002/marc.201300798

Fingerprint Dive into the research topics of 'Self-assembled microspheres driven by dipole-dipole interactions: UCST-type transition in water'. Together they form a unique fingerprint.

Cite this

@article{5f1bdc361bbe4d1699e2252e6d3ce3e3,

title = "Self-assembled microspheres driven by dipole-dipole interactions: UCST-type transition in water",

abstract = "A double hydrophilic block copolymer, poly(ethylene glycol)-poly(3-dimethyl (methacryloyloxyethyl) ammonium propane sulfonate) (PEG-SB), is synthesized by reversible addition-fragmentation transfer (RAFT) polymerization using PEG methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) as a chain transfer agent. PEG-SB forms multi-layered microspheres with dipole-dipole interactions of the SB side chains as the driving force. The PEG-SB polymers show an upper critical solution temperature (UCST) and the UCST is controllable by the polymerization degree. The PEG-SB microspheres are dissociated above the UCST and then monodispersed microspheres (∼1 μm) are obtained when the solution temperature is decreased below the UCST again. The disassociation/ association of the microspheres is also controllable using the concentration of NaCl. These multi-responsive microspheres could be a powerful tool in the field of nano-biotechnology.",

keywords = "dipole-dipole interactions, microspheres, self-assembly, stimuli-sensitive polymers, upper critical solution temperature",

author = "Nobuyuki Morimoto and Kanna Muramatsu and Tetsuichi Wazawa and Yuichi Inoue and Makoto Suzuki",

year = "2014",

month = jan,

doi = "10.1002/marc.201300798",

language = "English",

volume = "35",

pages = "103--108",

journal = "Macromolecular Rapid Communications",

issn = "1022-1336",

publisher = "Wiley-VCH Verlag",

number = "1",

}

TY - JOUR

T1 - Self-assembled microspheres driven by dipole-dipole interactions

T2 - UCST-type transition in water

AU - Morimoto, Nobuyuki

AU - Muramatsu, Kanna

AU - Wazawa, Tetsuichi

AU - Inoue, Yuichi

AU - Suzuki, Makoto

PY - 2014/1

Y1 - 2014/1

N2 - A double hydrophilic block copolymer, poly(ethylene glycol)-poly(3-dimethyl (methacryloyloxyethyl) ammonium propane sulfonate) (PEG-SB), is synthesized by reversible addition-fragmentation transfer (RAFT) polymerization using PEG methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) as a chain transfer agent. PEG-SB forms multi-layered microspheres with dipole-dipole interactions of the SB side chains as the driving force. The PEG-SB polymers show an upper critical solution temperature (UCST) and the UCST is controllable by the polymerization degree. The PEG-SB microspheres are dissociated above the UCST and then monodispersed microspheres (∼1 μm) are obtained when the solution temperature is decreased below the UCST again. The disassociation/ association of the microspheres is also controllable using the concentration of NaCl. These multi-responsive microspheres could be a powerful tool in the field of nano-biotechnology.

AB - A double hydrophilic block copolymer, poly(ethylene glycol)-poly(3-dimethyl (methacryloyloxyethyl) ammonium propane sulfonate) (PEG-SB), is synthesized by reversible addition-fragmentation transfer (RAFT) polymerization using PEG methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) as a chain transfer agent. PEG-SB forms multi-layered microspheres with dipole-dipole interactions of the SB side chains as the driving force. The PEG-SB polymers show an upper critical solution temperature (UCST) and the UCST is controllable by the polymerization degree. The PEG-SB microspheres are dissociated above the UCST and then monodispersed microspheres (∼1 μm) are obtained when the solution temperature is decreased below the UCST again. The disassociation/ association of the microspheres is also controllable using the concentration of NaCl. These multi-responsive microspheres could be a powerful tool in the field of nano-biotechnology.

KW - dipole-dipole interactions

KW - microspheres

KW - self-assembly

KW - stimuli-sensitive polymers

KW - upper critical solution temperature

UR - http://www.scopus.com/inward/record.url?scp=84891633155&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891633155&partnerID=8YFLogxK

U2 - 10.1002/marc.201300798

DO - 10.1002/marc.201300798

M3 - Article

C2 - 24307305

AN - SCOPUS:84891633155

VL - 35

SP - 103

EP - 108

JO - Macromolecular Rapid Communications

JF - Macromolecular Rapid Communications

SN - 1022-1336

IS - 1

ER -

Self-assembled microspheres driven by dipole-dipole interactions: UCST-type transition in water

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this