Selective Modification of the N-Terminal Structure of PolytheonamideB Significantly Changes its Cytotoxicity and Activity as an Ion Channel

Naoki Shinohara, Hiroaki Itoh, Shigeru Matsuoka, Masayuki Inoue

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)1770-1773
    Number of pages4
    JournalChemMedChem
    Volume7
    Issue number10
    DOIs
    Publication statusPublished - 2012 Oct

    Keywords

    • Cytotoxic agents
    • Natural products
    • Nonribosomal peptides
    • Structure-activity relationships
    • Synthetic ion channels

    ASJC Scopus subject areas

    • Biochemistry
    • Molecular Medicine
    • Pharmacology
    • Drug Discovery
    • Pharmacology, Toxicology and Pharmaceutics(all)
    • Organic Chemistry

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