Selective metallation of thiophene and thiazole rings with magnesium amide base

Manabu Shilai, Yoshinori Kondo, Takao Sakamoto

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

The chemoselective magnesiation of thiophene and thiazole derivatives were reported using magnesium chloride. Organomagnesium compounds were used at relatively higher temperatures. The results showed that hydrogen-magnesium exchange reaction of thiophene derivatives with iPr2NMgCl proceeded selectively.

Original languageEnglish
Pages (from-to)442-444
Number of pages3
JournalJournal of the Chemical Society. Perkin Transactions 1
Issue number4
DOIs
Publication statusPublished - 2001 Feb 21

ASJC Scopus subject areas

  • Chemistry(all)

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