When antineoplastic drugs are administered to a patient with impaired or unstable renal function, problems related to the dosage schedule may occur because of differences in pharmacokinetics between patients with normal renal function and those with renal dysfunction. We performed selective intraarterial infusion chemotherapy for a patient with maxillary squamous cell carcinoma who was undergoing hemodialysis for chronic renal failure. Cisplatin at doses of 50 mg/body and docetaxel at doses of 20 mg/body were administered via the maxillary artery twice at a one-week interval. The effect of intraarterial infusion chemotherapy was partial response. We could carry out the subsequential surgery and radiation therapy without severe adverse effects.
- Maxillary carcinoma
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