TY - JOUR
T1 - Selective impairment in the retrieval of family relationships in person identification
T2 - A case study of delusional misidentification
AU - Abe, Nobuhito
AU - Ishii, Hiroshi
AU - Fujii, Toshikatsu
AU - Ueno, Aya
AU - Lee, Eunjoo
AU - Ishioka, Toshiyuki
AU - Mori, Etsuro
N1 - Funding Information:
This work was supported by a research grant from the Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists to N.A. (05J04930). We are grateful to Yoshiyuki Hosokai, Yoichi Sawada, and Maki Suzuki for their assistance. We would also like to thank Yuko Meguro for referring the patient to us, and Kazumi Hirayama and Kenichi Meguro for their insightful comments. Finally, we would like to thank the patient and her family for contributing their valuable time to participate in this study.
PY - 2007
Y1 - 2007
N2 - We describe a 74-year-old, right-handed woman who exhibited a peculiar form of delusional misidentification due to Alzheimer's disease (AD) combined with idiopathic normal pressure hydrocephalus (iNPH). The patient's most distinctive symptom was that she often misidentified her daughters as her sisters. She had severe atrophy of the bilateral medial temporal lobe and right-hemisphere-dominant hypoperfusion in the fronto-temporo-parietal cortices. Detailed tests revealed that she had a selective deficit in retrieving the family relationships between herself and her daughters/husband (i.e., she misidentified her daughters as her sisters and her husband as her father), despite being able to retrieve the names and faces of her family members, and some person-specific semantic information (e.g., occupation) related to them. We speculate that this specific type of misidentification can be elicited by failure to update semantic memory through the encoding of new episodic memory due to right-hemisphere-dominant fronto-temporal dysfunction.
AB - We describe a 74-year-old, right-handed woman who exhibited a peculiar form of delusional misidentification due to Alzheimer's disease (AD) combined with idiopathic normal pressure hydrocephalus (iNPH). The patient's most distinctive symptom was that she often misidentified her daughters as her sisters. She had severe atrophy of the bilateral medial temporal lobe and right-hemisphere-dominant hypoperfusion in the fronto-temporo-parietal cortices. Detailed tests revealed that she had a selective deficit in retrieving the family relationships between herself and her daughters/husband (i.e., she misidentified her daughters as her sisters and her husband as her father), despite being able to retrieve the names and faces of her family members, and some person-specific semantic information (e.g., occupation) related to them. We speculate that this specific type of misidentification can be elicited by failure to update semantic memory through the encoding of new episodic memory due to right-hemisphere-dominant fronto-temporal dysfunction.
KW - Alzheimer's disease
KW - Delusional misidentification
KW - Idiopathic normal pressure hydrocephalus
KW - Person identification
UR - http://www.scopus.com/inward/record.url?scp=34548475524&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548475524&partnerID=8YFLogxK
U2 - 10.1016/j.neuropsychologia.2007.06.003
DO - 10.1016/j.neuropsychologia.2007.06.003
M3 - Article
C2 - 17655885
AN - SCOPUS:34548475524
VL - 45
SP - 2902
EP - 2909
JO - Neuropsychologia
JF - Neuropsychologia
SN - 0028-3932
IS - 13
ER -