To realize carbon-neutral energy-cycle system, we have started new JST, CREST project. Ethylene glycol was used as energy media, and selective ethylene glycol oxidation reaction was examined. When ethylene glycol is selectively oxidized to oxalic acid, reaction enthalpy, ΔrH, is -941 kJ/mol. This means that 79% of energy can be used compared to complete oxidation reaction. Liquid oxalic acid may be able to be photocatalytically reduced to ethylene glycol. In this study, direct-ethylene glycol fuel cells composed of NaCo2O4 and LaSr3Fe3O10 electrolytes and Pt/C, PtRu/C, Pd/C, and Fe-Co-Ni/C anode catalysts were examined. When Fe-Co-Ni/C is used, the fuel cell is completely noble metal free. The fuel cell generates a high output power density of 27 mW/cm2 at current density of 90 mA/cm2.