Selective capture of 1α,25-(OH)2-previtamin D3 utilizing polymer-supported trialkylsilyl triflate in the synthesis of 1α,25-(OH)2-vitamin D3

Takayuki Doi, Masahito Yoshida, Ichiro Hijikuro, Takashi Takahashi

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Catch and release method utilizing polymer-support was investigated in the separation of 1α,25-(OH)2 pre- and provitamin D3. Polymer-supported alkyldiisopropylsilyl triflate selectively captured the previtamin D3 from a 26:74 mixture of pre- and provitamin D 3 produced by photoisomerization of provitamin D3.

Original languageEnglish
Pages (from-to)5727-5729
Number of pages3
JournalTetrahedron Letters
Volume45
Issue number29
DOIs
Publication statusPublished - 2004 Jul 12

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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