Selective binding of steroids by 2,2′-biquinoline-4,4′-dicarboxamide-bridged bis(β-cyclodextrin): Fluorescence enhancement by guest inclusion

Yu Liu; Yun Song; Hao Wang; Heng Yi Zhang; Takehiko Wada; Yoshihisa Inoue

doi:10.1021/jo026908k

Selective binding of steroids by 2,2′-biquinoline-4,4′-dicarboxamide-bridged bis(β-cyclodextrin): Fluorescence enhancement by guest inclusion

Yu Liu, Yun Song, Hao Wang, Heng Yi Zhang, Takehiko Wada, Yoshihisa Inoue

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

A novel bis(β-cyclodextrin) was synthesized, and its binding behavior with steroids was investigated to demonstrate that the cooperative co-inclusion of guest and tether by two cyclodextrin moieties is operative to afford the highest molecular selectivity of up to 3.6 for deoxycholate over taurocholate.

Original language	English
Pages (from-to)	3687-3690
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	68
Issue number	9
DOIs	https://doi.org/10.1021/jo026908k
Publication status	Published - 2003 May 2
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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10.1021/jo026908k

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Selective binding of steroids by 2,2′-biquinoline-4,4′-dicarboxamide-bridged bis(β-cyclodextrin) : Fluorescence enhancement by guest inclusion. / Liu, Yu; Song, Yun; Wang, Hao; Zhang, Heng Yi; Wada, Takehiko; Inoue, Yoshihisa.

In: Journal of Organic Chemistry, Vol. 68, No. 9, 02.05.2003, p. 3687-3690.

Research output: Contribution to journal › Article › peer-review

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abstract = "A novel bis(β-cyclodextrin) was synthesized, and its binding behavior with steroids was investigated to demonstrate that the cooperative co-inclusion of guest and tether by two cyclodextrin moieties is operative to afford the highest molecular selectivity of up to 3.6 for deoxycholate over taurocholate.",

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AU - Wang, Hao

AU - Zhang, Heng Yi

AU - Wada, Takehiko

AU - Inoue, Yoshihisa

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AB - A novel bis(β-cyclodextrin) was synthesized, and its binding behavior with steroids was investigated to demonstrate that the cooperative co-inclusion of guest and tether by two cyclodextrin moieties is operative to afford the highest molecular selectivity of up to 3.6 for deoxycholate over taurocholate.

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Selective binding of steroids by 2,2′-biquinoline-4,4′-dicarboxamide-bridged bis(β-cyclodextrin): Fluorescence enhancement by guest inclusion

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