Abstract
Epithelia are tissues that regulate exchanges with the environment. They are very dynamic and can acquire virtually any shape; at the cellular level, they are composed of cells tightly connected by junctions. Most often epithelia are amenable to live imaging; however, the large number of cells composing an epithelium and the absence of informatics tools dedicated to epithelial analysis largely prevented tissue scale studies. Here we present Tissue Analyzer, a free tool that can be used to segment and analyze epithelial cells and monitor tissue dynamics.
| Original language | English |
|---|---|
| Title of host publication | Methods in Molecular Biology |
| Publisher | Humana Press Inc. |
| Pages | 227-239 |
| Number of pages | 13 |
| DOIs | |
| Publication status | Published - 2016 Jan 1 |
Publication series
| Name | Methods in Molecular Biology |
|---|---|
| Volume | 1478 |
| ISSN (Print) | 1064-3745 |
Keywords
- Cell tracking
- Cells
- Epithelia
- Junctional remodeling
- Junctions
- Live imaging
- Quantitative biology
- Segmentation
- Tissue analyzer
ASJC Scopus subject areas
- Molecular Biology
- Genetics
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Cite this
Aigouy, B., Umetsu, D., & Eaton, S. (2016). Segmentation and quantitative analysis of epithelial tissues. In Methods in Molecular Biology (pp. 227-239). (Methods in Molecular Biology; Vol. 1478). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-6371-3_13