Segmentation and quantitative analysis of epithelial tissues

Benoit Aigouy, Daiki Umetsu, Suzanne Eaton

    Research output: Chapter in Book/Report/Conference proceedingChapter

    49 Citations (Scopus)

    Abstract

    Epithelia are tissues that regulate exchanges with the environment. They are very dynamic and can acquire virtually any shape; at the cellular level, they are composed of cells tightly connected by junctions. Most often epithelia are amenable to live imaging; however, the large number of cells composing an epithelium and the absence of informatics tools dedicated to epithelial analysis largely prevented tissue scale studies. Here we present Tissue Analyzer, a free tool that can be used to segment and analyze epithelial cells and monitor tissue dynamics.

    Original languageEnglish
    Title of host publicationMethods in Molecular Biology
    PublisherHumana Press Inc.
    Pages227-239
    Number of pages13
    DOIs
    Publication statusPublished - 2016 Jan 1

    Publication series

    NameMethods in Molecular Biology
    Volume1478
    ISSN (Print)1064-3745

    Keywords

    • Cell tracking
    • Cells
    • Epithelia
    • Junctional remodeling
    • Junctions
    • Live imaging
    • Quantitative biology
    • Segmentation
    • Tissue analyzer

    ASJC Scopus subject areas

    • Molecular Biology
    • Genetics

    Fingerprint

    Dive into the research topics of 'Segmentation and quantitative analysis of epithelial tissues'. Together they form a unique fingerprint.

    Cite this