Segmentation and quantitative analysis of epithelial tissues

Benoit Aigouy, Daiki Umetsu, Suzanne Eaton

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Citations (Scopus)

Abstract

Epithelia are tissues that regulate exchanges with the environment. They are very dynamic and can acquire virtually any shape; at the cellular level, they are composed of cells tightly connected by junctions. Most often epithelia are amenable to live imaging; however, the large number of cells composing an epithelium and the absence of informatics tools dedicated to epithelial analysis largely prevented tissue scale studies. Here we present Tissue Analyzer, a free tool that can be used to segment and analyze epithelial cells and monitor tissue dynamics.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages227-239
Number of pages13
DOIs
Publication statusPublished - 2016 Jan 1

Publication series

NameMethods in Molecular Biology
Volume1478
ISSN (Print)1064-3745

Keywords

  • Cell tracking
  • Cells
  • Epithelia
  • Junctional remodeling
  • Junctions
  • Live imaging
  • Quantitative biology
  • Segmentation
  • Tissue analyzer

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Aigouy, B., Umetsu, D., & Eaton, S. (2016). Segmentation and quantitative analysis of epithelial tissues. In Methods in Molecular Biology (pp. 227-239). (Methods in Molecular Biology; Vol. 1478). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-6371-3_13