Secondary Amyloidosis Associated with Castleman's Disease

Katsuhiro Tanaka; Masakazu Horita; Hitoshi Shibayama; Masataka Seike; Yasuko Itoh; Kazuyuki Hamaguchi; Yasufumi Sato; Toshiie Sakata; Tetsuya Ishida

doi:10.2169/internalmedicine.34.122

Secondary Amyloidosis Associated with Castleman's Disease

Katsuhiro Tanaka, Masakazu Horita, Hitoshi Shibayama, Masataka Seike, Yasuko Itoh, Kazuyuki Hamaguchi, Yasufumi Sato, Toshiie Sakata, Tetsuya Ishida

New Industry Creation Hatchery Center (NICHe)

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A rare case of secondary amyloidosis associated with Castleman's disease is reported. A 53-year-old woman was referred for investigation of proteinuria. Biopsy specimens from kidney and gastric mucosa revealed numerous amyloid deposits, denned as AA amyloidosis by immunohistological staining. Castleman's disease was found in the abdomen as the primary disease for the amyloidosis. Although the urinary protein was somewhat reduced and the inflammatory findings were improved after removal of the lymphoma, renal insufficiency progressed and hemodialysis was begun.

Original language	English
Pages (from-to)	122-126
Number of pages	5
Journal	Internal Medicine
Volume	34
Issue number	2
DOIs	https://doi.org/10.2169/internalmedicine.34.122
Publication status	Published - 1995

Keywords

renal insufficiency
serum amyloid protein A

ASJC Scopus subject areas

Internal Medicine

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abstract = "A rare case of secondary amyloidosis associated with Castleman's disease is reported. A 53-year-old woman was referred for investigation of proteinuria. Biopsy specimens from kidney and gastric mucosa revealed numerous amyloid deposits, denned as AA amyloidosis by immunohistological staining. Castleman's disease was found in the abdomen as the primary disease for the amyloidosis. Although the urinary protein was somewhat reduced and the inflammatory findings were improved after removal of the lymphoma, renal insufficiency progressed and hemodialysis was begun.",

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T1 - Secondary Amyloidosis Associated with Castleman's Disease

AU - Tanaka, Katsuhiro

AU - Horita, Masakazu

AU - Shibayama, Hitoshi

AU - Seike, Masataka

AU - Itoh, Yasuko

AU - Hamaguchi, Kazuyuki

AU - Sato, Yasufumi

AU - Sakata, Toshiie

AU - Ishida, Tetsuya

PY - 1995

Y1 - 1995

N2 - A rare case of secondary amyloidosis associated with Castleman's disease is reported. A 53-year-old woman was referred for investigation of proteinuria. Biopsy specimens from kidney and gastric mucosa revealed numerous amyloid deposits, denned as AA amyloidosis by immunohistological staining. Castleman's disease was found in the abdomen as the primary disease for the amyloidosis. Although the urinary protein was somewhat reduced and the inflammatory findings were improved after removal of the lymphoma, renal insufficiency progressed and hemodialysis was begun.

AB - A rare case of secondary amyloidosis associated with Castleman's disease is reported. A 53-year-old woman was referred for investigation of proteinuria. Biopsy specimens from kidney and gastric mucosa revealed numerous amyloid deposits, denned as AA amyloidosis by immunohistological staining. Castleman's disease was found in the abdomen as the primary disease for the amyloidosis. Although the urinary protein was somewhat reduced and the inflammatory findings were improved after removal of the lymphoma, renal insufficiency progressed and hemodialysis was begun.

KW - renal insufficiency

KW - serum amyloid protein A

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