Salt effect on partition coefficient of glycine, L-valine, and L-phenyl alanine in n-octanol-water system

Chiaki Yokoyama, Masato Terui, Shinji Takahashi

Research output: Contribution to journalConference articlepeer-review

7 Citations (Scopus)

Abstract

The n-octanol-water partition coefficient is an important property to measure the hydrophobicity of organic compounds, which has been demonstrated to be a parameter in studying the conformation of biomolecules in aqueous solutions. The hydrophobic parameters of the amino acid side chains of peptides have been evaluated from the n-octanol-water partition coefficients of amino acids. For biological systems, electrolytes play an important role on thermodynamic properties. Numerous measurements of the partition coefficients of amino acids in the n-octanol-water system have been already made but without any salt effect. In this study, we investigated the salt effect on the n-octanol-water partition coefficients of glycine, L-valine, and L-phenyl alanine with the use of a generator column. The electrolytes used were LiCl, NaCl, and Na2SO4.

Original languageEnglish
Pages (from-to)283-290
Number of pages8
JournalFluid Phase Equilibria
Volume82
Issue numberpt 1
DOIs
Publication statusPublished - 1993 Feb 1
EventProceedings of the 6th International Conference on Fluid Properties and Phase Equilibria for Chemical Process Design 1992 - Cortina d'Ampezzo, Italy
Duration: 1992 Jul 191992 Jul 24

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Fingerprint Dive into the research topics of 'Salt effect on partition coefficient of glycine, L-valine, and L-phenyl alanine in n-octanol-water system'. Together they form a unique fingerprint.

Cite this