S-20-5 Imaging of Neurotransmitter Receptors in the Living Human Brain by Positron Emission Tomography (PET)

K. Yanai, T. Watanabe, M. Itoh, T. Ido

Research output: Contribution to journalArticlepeer-review

Abstract

Various brain imaging techniques such as X-ray computerized tomography and magnet i c resonance imaging have become available in the past decade. Posi tron emission tomography (PET) is a new and unique approach to identify neurotransmitter receptors in the 1iving human brain [1]. Dopamine Di and D2, serotonin 5HT2, muscarinic cholinergic, opiate, benzodiazepine, histamine Hi receptors, and monoamine oxidases (A and B) have been targets of PET studies in the 1iving human brain [1,2]. We have successfully imaged hi stamine Hi receptors using CX1C]-pyri lamine (or mepyramine), an ant ihistaminic, or [1;LC]-doxep i ne, a tricyclic ant idepressant with a potent ant ihi staminic action, by PET [3-5]. The present art icle gives an out line of concept s to visualize neurotransmi t ter receptors in the living human brain by PET on the basi s of our ori ginal works.

Original languageEnglish
Pages (from-to)581-584
Number of pages4
JournalJournal of nutritional science and vitaminology
Volume38
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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