Ruptured atherosclerotic plaque distant from maximal stenosis in acute myocardial infarction

Osamu Seguchi, Akiko Maehara, Isao Morii, Yoritaka Otsuka, Satoshi Yasuda, Shunichi Miyazaki, Masakazu Yamagishi

Research output: Contribution to journalArticlepeer-review


We describe a patient with acute myocardial infarction who showed ruptured plaque distant from the maximally stenotic lesion. In a 54-year-old male patient with acute antero-lateral myocardial infarction, coronary angiography showed a resolution of occlusive lesion with residual stenotic lesion in the middle portion of the left anterior descending artery (LAD) following t-PA administration. One month later, coronary angiography again disclosed significant stenosis of the middle LAD. Intravascular ultrasound revealed ruptured plaque that was located proximal to the maximally stenotic site which is generally considered as the culprit lesion. In this case, transient vessel occlusion occurred at the maximally stenotic site probably associated with plaque rupture distant from this lesion.

Original languageEnglish
Pages (from-to)53-55
Number of pages3
JournalInternal Medicine
Issue number1
Publication statusPublished - 2003 Jan 1
Externally publishedYes


  • Acute coronary syndrome
  • Intravascular ultrasound
  • Plaque rupture
  • Unstable Plaque

ASJC Scopus subject areas

  • Internal Medicine


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