Rotavirus gastro-enteritis in hospitalized children with acute diarrhoea in Zambia

M. Mpabalwani, H. Oshitani, F. Kasolo, K. Mizuta, N. Luo, N. Matsubayashi, G. Bhat, H. Suzuki, Y. Numazaki

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The clinical and epidemiological aspects of rotavirus diarrhoea were studied in hospitalized children with acute diarrhoea in Lusaka, Zambia. Two hundred and fifty-six (24.0%) of 1069 children admitted to the study were shedding rotavirus. The rotavirus-positive rate was highest in children less than 1 year of age (37.0%) and it was also high in those less than 6 months old. Rotavirus diarrhoea was seen throughout the year with a higher rotavirus-positive rate in the dry season. In rotavirus-positive diarrhoea patients, more children were dehydrated (82.4%) than in the rotavirus-negative group (56.2%). Rotavirus infection was more common in the children with normal nutritional status (27.6%, 162/588) than in chose with malnutrition (19.3%, 93/482). The associated case fatality rate in the rotavirus-positive group was 6.4%, significantly less than in the rotavirus-negative group (OR 0.44, 95% CI 0.24-0.79), and mortality cases were seen only in children less than 2 years old.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalAnnals of Tropical Paediatrics
Volume15
Issue number1
DOIs
Publication statusPublished - 1995 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Rotavirus gastro-enteritis in hospitalized children with acute diarrhoea in Zambia'. Together they form a unique fingerprint.

  • Cite this

    Mpabalwani, M., Oshitani, H., Kasolo, F., Mizuta, K., Luo, N., Matsubayashi, N., Bhat, G., Suzuki, H., & Numazaki, Y. (1995). Rotavirus gastro-enteritis in hospitalized children with acute diarrhoea in Zambia. Annals of Tropical Paediatrics, 15(1), 39-43. https://doi.org/10.1080/02724936.1995.11747747