Role of SraP in adherence of Staphylococcus aureus to the bovine mammary epithelia

Daisuke Takamatsu; Eiji Hata; Makoto Osaki; Hisashi Aso; Sota Kobayashi; Tsutomu Sekizaki

doi:10.1292/jvms.70.735

Role of SraP in adherence of Staphylococcus aureus to the bovine mammary epithelia

Daisuke Takamatsu, Eiji Hata, Makoto Osaki, Hisashi Aso, Sota Kobayashi, Tsutomu Sekizaki

AGR - Life Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

SraP, a platelet-binding surface protein of Staphylococcus aureus, is involved in the pathogenesis of infective endocarditis. In this study, we investigated the importance of SraP in the pathogenesis of bovine mastitis. By means of PCR, sraP was detected in all the isolates tested from bovine bulk milk and humans. However, SraP was not expressed on the cell surface in half of the bovine isolates. Moreover, disruption of sraP did not affect the ability of S. aureus to adhere to cultured bovine mammary epithelial cells. These results suggest that SraP does not seem to be an important factor for S. aureus to adhere to the bovine mammary epithelia.

Original language	English
Pages (from-to)	735-738
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	70
Issue number	7
DOIs	https://doi.org/10.1292/jvms.70.735
Publication status	Published - 2008 Jul

Keywords

Bovine mammary epithelial cell
SraP
Staphylococcus aureus

ASJC Scopus subject areas

veterinary(all)

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10.1292/jvms.70.735

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abstract = "SraP, a platelet-binding surface protein of Staphylococcus aureus, is involved in the pathogenesis of infective endocarditis. In this study, we investigated the importance of SraP in the pathogenesis of bovine mastitis. By means of PCR, sraP was detected in all the isolates tested from bovine bulk milk and humans. However, SraP was not expressed on the cell surface in half of the bovine isolates. Moreover, disruption of sraP did not affect the ability of S. aureus to adhere to cultured bovine mammary epithelial cells. These results suggest that SraP does not seem to be an important factor for S. aureus to adhere to the bovine mammary epithelia.",

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AU - Takamatsu, Daisuke

AU - Hata, Eiji

AU - Osaki, Makoto

AU - Aso, Hisashi

AU - Kobayashi, Sota

AU - Sekizaki, Tsutomu

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AB - SraP, a platelet-binding surface protein of Staphylococcus aureus, is involved in the pathogenesis of infective endocarditis. In this study, we investigated the importance of SraP in the pathogenesis of bovine mastitis. By means of PCR, sraP was detected in all the isolates tested from bovine bulk milk and humans. However, SraP was not expressed on the cell surface in half of the bovine isolates. Moreover, disruption of sraP did not affect the ability of S. aureus to adhere to cultured bovine mammary epithelial cells. These results suggest that SraP does not seem to be an important factor for S. aureus to adhere to the bovine mammary epithelia.

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