Role of selective arterial secretin injection test in treatment of gastrinoma

Chikashi Shibata, Yuji Funayama, Kouhei Fukushima, Ken Ichi Takahashi, Tatsuya Ueno, Munenori Nagao, Sho Haneda, Kazuhiro Watanabe, Katsuyoshi Kudoh, Atsushi Kohyama, Hiroo Naito, Iwao Sasaki

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background/Aims: To study whether use of the selective arterial secretin injection test increased the rate of tumor localization and curative resection in patients with gastrinoma. Methodology: Nine patients with gastrinoma were divided into 2 groups, before and after introduction of selective arterial secretin injection test; 4 patients before 1987 (Group 1) and 5 patients after 1988 (Group 2). Clinical results were compared retrospectively between groups. Results: Localization of primary gastrinoma was made with conventional imaging studies in 1 of the 4 patients in Group 1 and 3 of the 5 patients in Group 2. In contrast, use of the selective arterial secretin injection test was able to localize the primary tumor in 4 of the 5 patients in Group 2. Total gastrectomy was carried out in the 4 patients in Group 1, and pancreatoduodenectomy was the most frequently performed procedure (3 patients) in Group 2. Rate of curative resection was 25% and 80% in Groups 1 and 2, respectively. Conclusions: These results indicate that combining selective arterial secretin injection test with conventional imaging studies contributes to increasing rate of curative resection of gastrinoma.

Original languageEnglish
Pages (from-to)960-963
Number of pages4
JournalHepato-Gastroenterology
Volume53
Issue number72
Publication statusPublished - 2006 Nov

Keywords

  • Gastrinoma
  • Selective arterial injection test
  • Zollinger-ellison syndrome

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint Dive into the research topics of 'Role of selective arterial secretin injection test in treatment of gastrinoma'. Together they form a unique fingerprint.

Cite this