Abstract
The ETS family of transcription factors is defined by a conserved DNA-binding ETS domain that forms a winged helix-turn-helix structural motif. This family of transcription factors is involved in a diverse array of biological functions including cellular growth and differentiation, as well as organ development. Among the members of this family, ETS-1, ERG, Fli-1, TEL, and NERF-2 are expressed in endothelial cells and their progenitors. This review will summarize the role of ETS family transcription factors in vascular development and angiogenesis.
| Original language | English |
|---|---|
| Pages (from-to) | 19-24 |
| Number of pages | 6 |
| Journal | Cell structure and function |
| Volume | 26 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2001 |
Keywords
- Angiogenesis
- ETS
- Transcription factor
- Vasculogenesis
ASJC Scopus subject areas
- Physiology
- Molecular Biology
- Cell Biology