TY - JOUR
T1 - Role of ETS family transcription factors in vascular development and angiogenesis
AU - Sato, Y.
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - The ETS family of transcription factors is defined by a conserved DNA-binding ETS domain that forms a winged helix-turn-helix structural motif. This family of transcription factors is involved in a diverse array of biological functions including cellular growth and differentiation, as well as organ development. Among the members of this family, ETS-1, ERG, Fli-1, TEL, and NERF-2 are expressed in endothelial cells and their progenitors. This review will summarize the role of ETS family transcription factors in vascular development and angiogenesis.
AB - The ETS family of transcription factors is defined by a conserved DNA-binding ETS domain that forms a winged helix-turn-helix structural motif. This family of transcription factors is involved in a diverse array of biological functions including cellular growth and differentiation, as well as organ development. Among the members of this family, ETS-1, ERG, Fli-1, TEL, and NERF-2 are expressed in endothelial cells and their progenitors. This review will summarize the role of ETS family transcription factors in vascular development and angiogenesis.
KW - Angiogenesis
KW - ETS
KW - Transcription factor
KW - Vasculogenesis
UR - http://www.scopus.com/inward/record.url?scp=0035019487&partnerID=8YFLogxK
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U2 - 10.1247/csf.26.19
DO - 10.1247/csf.26.19
M3 - Review article
C2 - 11345500
AN - SCOPUS:0035019487
VL - 26
SP - 19
EP - 24
JO - Cell Structure and Function
JF - Cell Structure and Function
SN - 0386-7196
IS - 1
ER -