Role of chronic Pseudomonas aeruginosa infection in the development of bronchiectasis

M. Nagaki, S. Shimura, Y. Tanno, T. Ishibashi, H. Sasaki, T. Takishima

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

To understand the role of Pseudomonas aeruginosa infection in the development of bronchiectasis, we investigated by CT the presence of bronchiectasis in two groups of chronic bronchitis patients and in a control group. There were no differences in clinical or laboratory findings between groups A and B. Three observers without any knowledge of these patients reported bronchiectasis on a scale of 0 to 3 and bronchial wall thickness on a scale of 0 to 3 in each lobe of both lungs. Bronchiectasis and wall thickness scores in group A (chronic bronchitis with P aeruginosa infection) were significantly higher than bronchiectasis scores and wall thickness in group B (chronic bronchitis without P aeruginosa infection). Both scores in group B were higher than those in group C (control group). These findings support the idea that chronic P aeruginosa infection plays a role in the development of bronchiectasis.

Original languageEnglish
Pages (from-to)1464-1469
Number of pages6
JournalChest
Volume102
Issue number5
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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    Nagaki, M., Shimura, S., Tanno, Y., Ishibashi, T., Sasaki, H., & Takishima, T. (1992). Role of chronic Pseudomonas aeruginosa infection in the development of bronchiectasis. Chest, 102(5), 1464-1469. https://doi.org/10.1378/chest.102.5.1464