Role of acetylcholine receptor subunits in gating of the channel

Bert Sakmann, Christoph Methfessel, Masayoshi Mishina, Tomoyuki Takahashi, Toshiyuki Takai, Masaaki Kurasaki, Kazuhiko Fukuda, Shosaku Numa

Research output: Contribution to journalArticlepeer-review

166 Citations (Scopus)

Abstract

The Torpedo and calf acetylcholine receptors and hybrids composed of subunits from the two species have been produced in Xenopus oocytes by the use of the cloned complementary DNAs. Single-channel current measurements indicate that these receptors form channels of similar conductance but with different gating behaviour.

Original languageEnglish
Pages (from-to)538-543
Number of pages6
JournalNature
Volume318
Issue number6046
DOIs
Publication statusPublished - 1985 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • General

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