Risk factors for surgical site infection in Japanese patients with ulcerative colitis: A multicenter prospective study

Toshimitsu Araki, Yoshiki Okita, Motoi Uchino, Hiroki Ikeuchi, Iwao Sasaki, Yuji Funayama, Kouhei Fukushima, Kitarou Futami, Kiyoshi Maeda, Tsuneo Iiai, Michio Itabashi, Kazuo Hase, Satoshi Motoya, Atsuo Kitano, Tsunekazu Mizushima, Kotaro Maeda, Minako Kobayashi, Yasuhiko Mohri, Masato Kusunoki

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Purpose: A prospective, multicenter, observational study was performed to investigate the risk factors of surgical site infection (SSI) in patients with ulcerative colitis (UC). Methods: From 2009 to 2010, perioperative clinicopathological data were collected from patients who had undergone surgery for UC within the research period, for up to 6 consecutive months in 13 hospitals in Japan. The primary outcome was the development of SSI. Results: A total of 195 patients with UC who underwent colorectal surgery were enrolled. SSI was diagnosed in 38 (19.5 %) patients, in the form of incisional infection in 23 (11.8 %), organ/space infection in 16 (8.2 %), and both in 1 (0.5 %). There were no significant risk factors associated with an increased risk of development of incisional SSI. An American Society of Anesthesiologists physical status of ≥ 3 was indicated as the only significant risk factor for organ/space SSI (P = 0.02) compared with other factors, such as a neutrophil count of >100 × 102/mm3, albumin level of <3.5 g/dl, perioperative packed red blood cell transfusion, fair or poor colonic cleanliness, and therapeutic use of antibiotics. Conclusion: Poor general physical status was the significant independent risk factor for organ/space SSI in patients with UC in Japan.

Original languageEnglish
Pages (from-to)1072-1078
Number of pages7
JournalSurgery today
Issue number6
Publication statusPublished - 2014 Jun


  • Complication
  • Multicenter surveillance
  • Surgical site infection
  • Ulcerative colitis

ASJC Scopus subject areas

  • Surgery


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