TY - JOUR
T1 - Risk factors for recurrence and re-recurrence of ovarian endometriomas after laparoscopic excision
AU - Hayasaka, Shinichi
AU - Ugajin, Tomohisa
AU - Fujii, Osamu
AU - Nabeshima, Hiroshi
AU - Utsunomiya, Hiroki
AU - Yokomizo, Rei
AU - Yuki, Hiromithu
AU - Terada, Yukihiro
AU - Murakami, Takashi
AU - Yaegashi, Nobuo
PY - 2011/6/1
Y1 - 2011/6/1
N2 - Aim: Since ovarian endometrioma is frequently diagnosed in women of reproductive age, laparoscopic excision of the endometrioma is performed for most cases. However, endometriomas frequently recurs even after repeated surgical procedures. The aim of our study is to identify risk factors for recurrence and re-recurrence of endometriomas after the first and second laparoscopic excision. Material & Methods: We retrospectively evaluated 173 patients who had a minimum of one year postoperative follow-up after the laparoscopic excision of endometriomas. Ten and eight factors were evaluated to assess their effect on the risk of recurrence and re-recurrence, respectively. Factors were analyzed using univariate and the Cox regression test. Results: The overall rate of recurrence and re-recurrence were 45.1% and 45.5%, respectively. A high revised American Society for Reproductive Medicine score (1997) was associated with an increased risk of recurrence. Only postoperative pregnancy was associated with a decreased risk of recurrence. Short periods of normal menstruation without pregnancy or gonadotrophin-releasing hormone analogues from first surgery to recurrence were associated with higher rate of re-recurrence. Conclusions: A high revised American Society for Reproductive Medicine score was a risk factor, and postoperative pregnancy was protective against recurrence. The patient with short periods of normal menstruation without pregnancy or gonadotrophin-releasing hormone analogues from first surgery to recurrence had a high risk of re-recurrence.
AB - Aim: Since ovarian endometrioma is frequently diagnosed in women of reproductive age, laparoscopic excision of the endometrioma is performed for most cases. However, endometriomas frequently recurs even after repeated surgical procedures. The aim of our study is to identify risk factors for recurrence and re-recurrence of endometriomas after the first and second laparoscopic excision. Material & Methods: We retrospectively evaluated 173 patients who had a minimum of one year postoperative follow-up after the laparoscopic excision of endometriomas. Ten and eight factors were evaluated to assess their effect on the risk of recurrence and re-recurrence, respectively. Factors were analyzed using univariate and the Cox regression test. Results: The overall rate of recurrence and re-recurrence were 45.1% and 45.5%, respectively. A high revised American Society for Reproductive Medicine score (1997) was associated with an increased risk of recurrence. Only postoperative pregnancy was associated with a decreased risk of recurrence. Short periods of normal menstruation without pregnancy or gonadotrophin-releasing hormone analogues from first surgery to recurrence were associated with higher rate of re-recurrence. Conclusions: A high revised American Society for Reproductive Medicine score was a risk factor, and postoperative pregnancy was protective against recurrence. The patient with short periods of normal menstruation without pregnancy or gonadotrophin-releasing hormone analogues from first surgery to recurrence had a high risk of re-recurrence.
KW - Laparoscopic excision
KW - Ovarian endometriomas
KW - Re-recurrence
KW - Recurrence
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=80052747370&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052747370&partnerID=8YFLogxK
U2 - 10.1111/j.1447-0756.2010.01409.x
DO - 10.1111/j.1447-0756.2010.01409.x
M3 - Article
C2 - 21159045
AN - SCOPUS:80052747370
VL - 37
SP - 581
EP - 585
JO - Journal of Obstetrics and Gynaecology Research
JF - Journal of Obstetrics and Gynaecology Research
SN - 1341-8076
IS - 6
ER -