空腹血糖受损的社区老年人群三年后发生糖尿病的危险因素

Translated title of the contribution: Risk factors for developing diabetes after 3 years among community-dwelling elderly with impaired fasting glucose

Wen Zhang, Xiaolong Yang, Peipei Han, Yixuan Ma, Liyuan Fu, Liye Jia, Hairui Yu, Xiaoyu Chen, Lu Wang, Lin Hou, Xing Yu, Masahiro Kohzuki, Qi Guo

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background: The aim of the present study was to examine the risk factors for developing diabetes after 3 years in an elderly Chinese suburban population with impaired fasting glucose (IFG). Methods: The study population comprised residents of the Hangu area of Tianjin, China, with IFG, aged ≥60 years, who joined the national free physical examination program (n = 328; mean [±SD] age 68.0 ±6.1 years; 48.2% men). Diabetes was defined by self-report of a physician's diagnosis or fasting plasma glucose (FPG) ≥7.0 mmol/L; IFG was defined as FPG ≥5.6 and < 7.0 mmol/L. Risk factors of incident diabetes at the 3-year follow-up were analyzed individually using logistic regression analysis. Results: Between baseline and the 3-year follow-up, 56 subjects with IFG at baseline had developed diabetes. After multivariate adjustment for demographic and clinical factors, the incidence of diabetes increased with higher FPG (odds ratio [OR] 9.30, 95% confidence interval [CI] 2.84–30.48), but decreased with the grip strength/weight ratio (OR 0.88, 95% CI 0.82–0.94). Moreover, the combination of higher FPG and lower grip strength/weight was associated with a higher incidence of diabetes than higher FPG only or lower grip strength/weight (P < 0.05). Conclusion: The present study indicates that higher FPG and lower muscle strength are associated with glycemic deterioration among subjects with IFG after 3 years. The results suggest that not only glucose levels, but also physical performance may be useful markers of the risk of diabetes in this population.

Translated title of the contributionRisk factors for developing diabetes after 3 years among community-dwelling elderly with impaired fasting glucose
Original languageChinese
Pages (from-to)107-114
Number of pages8
JournalJournal of Diabetes
Volume11
Issue number2
DOIs
Publication statusPublished - 2019 Feb 1

Keywords

  • elderly
  • impaired fasting glucose
  • muscle strength

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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