Ripasudil eyedrops ameliorated bullous keratopathy complicated with cytomegalovirus corneal endotheliitis: a case report

Masaaki Yoshida, Shunji Yokokura, Takehiro Hariya, Wataru Kobayashi, Kazuki Hashimoto, Toru Nakazawa

Research output: Contribution to journalLetterpeer-review

Abstract

Purpose: We describe a case of bullous keratopathy complicated with cytomegalovirus (CMV) corneal endotheliitis that was successfully treated with ripasudil eye drops. Methods: A retrospective case report. Results: A 65-year-old female patient diagnosed with CMV-associated anterior uveitis in the right eye was referred to us when anterior uveitis recurred with bullous keratopathy. Initial best-corrected visual acuity (BCVA) was 0.4 (decimal visual acuity). Her condition did not improve with anti-CMV treatment, and BCVA decreased to 0.07. At this point, intraocular pressure (IOP) was 20 mmHg, and ripasudil eye drops were started for IOP control. After 1 month, not only had IOP decreased to 14 mm Hg but the condition of the corneal edema had also improved. The central corneal thickness decreased to a normal level, and the BCVA recovered to 0.8. Conclusion: Ripasudil eye drops not only lower IOP in patients with CMV corneal endotheliitis but may also have the potential to treat bullous keratopathy.

Original languageEnglish
JournalOcular Immunology and Inflammation
DOIs
Publication statusAccepted/In press - 2021
Externally publishedYes

Keywords

  • Bullous keratopathy
  • Corneal endotheliitis
  • cytomegalovirus
  • ripasudil
  • rock inhibitors

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

Fingerprint

Dive into the research topics of 'Ripasudil eyedrops ameliorated bullous keratopathy complicated with cytomegalovirus corneal endotheliitis: a case report'. Together they form a unique fingerprint.

Cite this