Rigidity sensing explained by active matter theory

Philippe Marcq, Natsuhiko Yoshinaga, Jacques Prost

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. We rationalize this observation using active matter theory, and propose that adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.

Original languageEnglish
Pages (from-to)L33-L35
JournalBiophysical Journal
Volume101
Issue number6
DOIs
Publication statusPublished - 2011 Sep 21
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics

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