Abstract
The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. We rationalize this observation using active matter theory, and propose that adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.
Original language | English |
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Pages (from-to) | L33-L35 |
Journal | Biophysical Journal |
Volume | 101 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2011 Sep 21 |
Externally published | Yes |
ASJC Scopus subject areas
- Biophysics