TY - JOUR
T1 - Right temporal-lobe contribution to the retrieval of family relationships in person identification
AU - Abe, Nobuhito
AU - Fujii, Toshikatsu
AU - Ueno, Aya
AU - Shigemune, Yayoi
AU - Suzuki, Maki
AU - Tashiro, Manabu
AU - Mori, Etsuro
N1 - Funding Information:
This work was partially supported by a Grant-in-Aid for Scientific Research on Priority Areas – System study on higher-order brain functions – from the Ministry of Education, Culture, Sports, Science and Technology of Japan (20020004 to E.M.), a Grant-in Aid for Scientific Research B# (21300101 to T.F.) and a Grant-in-Aid for Young Scientists (Start-up) (20800006 to N.A.) from the Japan Society for the Promotion of Science . This work was also partially supported by a JST grant on research and education in molecular imaging, and the Global COE Program (Basic & Translational Research Center for Global Brain Science, MEXT, Japan). Some of the experimental results were obtained using supercomputing resources at the Information Synergy Center, Tohoku University.
PY - 2010/12/3
Y1 - 2010/12/3
N2 - We previously reported a patient who exhibited a peculiar form of delusional misidentification. She had a selective deficit in retrieving family relationships between herself and her daughters and husband (i.e., she misidentified her daughters as her sisters and her husband as her father) despite being able to retrieve their names and faces and some person-specific semantic information (e.g., occupation). Based on this finding, the present positron emission tomography study was designed to elucidate the brain mechanisms underlying the retrieval of family relationships in healthy individuals. We found that the right inferior temporal gyrus, in which hypoperfusion was detected in the patient we had reported, was significantly activated during the retrieval of family relationships compared with names and occupations. These findings indicate that the retrieval of the relationships between oneself and one's family members may require a specific cognitive process dissociated from the retrieval of names and other person-specific semantic information.
AB - We previously reported a patient who exhibited a peculiar form of delusional misidentification. She had a selective deficit in retrieving family relationships between herself and her daughters and husband (i.e., she misidentified her daughters as her sisters and her husband as her father) despite being able to retrieve their names and faces and some person-specific semantic information (e.g., occupation). Based on this finding, the present positron emission tomography study was designed to elucidate the brain mechanisms underlying the retrieval of family relationships in healthy individuals. We found that the right inferior temporal gyrus, in which hypoperfusion was detected in the patient we had reported, was significantly activated during the retrieval of family relationships compared with names and occupations. These findings indicate that the retrieval of the relationships between oneself and one's family members may require a specific cognitive process dissociated from the retrieval of names and other person-specific semantic information.
KW - Family relationships
KW - Person identification
KW - Positron emission tomography (PET)
KW - Semantic memory
KW - Temporal lobe
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U2 - 10.1016/j.neulet.2010.09.031
DO - 10.1016/j.neulet.2010.09.031
M3 - Article
C2 - 20851168
AN - SCOPUS:77957889925
VL - 486
SP - 10
EP - 13
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 1
ER -