Rhodium-catalyzed cycloisomerization of allyl propargyl ethers: An efficient synthesis of 3,4-disubstituted furans

Hiroshi Kawai, Shuichi Oi, Yoshio Inoue

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Cycloisomerization of allyl propargyl ethers was found to be catalyzed by a cationic rhodium complex to give 3,4-disubstituted furans in one step. Addition of carboxylic acids to the reaction improved the yield of the products. Generation of a rhodium hydride species from a rhodium complex with the carboxylic acids followed by hydrorhodation of the substrate with the rhodium hydride species would be involved in the reaction pathway.

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalHeterocycles
Volume67
Issue number1
DOIs
Publication statusPublished - 2006 Jan 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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