Abstract
The addition of aryldifluoromethylsilanes to N-sulfonylaldimines was found to be catalyzed by a rhodium complex, [Rh(cod)(MeCN)2]BF4, in the presence of potassium fluoride to give the corresponding arylated N-sulfonylamines in good yield. The reaction mechanism would involve the generation of a fluoride-coordinated arylsilicate and the transmetalation between the arylsilicate and the rhodium complex to give the arylrhodium species as a key intermediate.
Original language | English |
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Pages (from-to) | 4855-4857 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 25 |
DOIs | |
Publication status | Published - 2004 Jun 14 |
Keywords
- Aldimines
- Arylation
- Arylsilanes
- Rhodium catalyst
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry