Rh(III)-catalyzed regioselective functionalization of C-H bonds of naphthylcarbamates for oxidative annulation with alkynes

Xuan Zhang, Weili Si, Ming Bao, Naoki Asao, Yoshinori Yamamoto, Tienan Jin

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

A Rh(III)-catalyzed highly efficient and regioselective functionalization of diverse C-H bonds of naphthylcarbamates for oxidative annulation with alkynes has been developed. The annulation with a neutral rhodium catalyst system proceeds through peri C-H bond functionalization of arylcarbamates to give benzoquinoline derivatives, while with a cationic rhodium catalyst system it proceeds through ortho C-H functionalization of arylcarbamates to furnish benzoindole derivatives.

Original languageEnglish
Pages (from-to)4830-4833
Number of pages4
JournalOrganic letters
Volume16
Issue number18
DOIs
Publication statusPublished - 2014 Sep 19

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Rh(III)-catalyzed regioselective functionalization of C-H bonds of naphthylcarbamates for oxidative annulation with alkynes'. Together they form a unique fingerprint.

Cite this