Reye's syndrome with cortical laminar necrosis: MRI

T. Kinoshita, S. Takahashi, K. Ishii, S. Higano, K. Matsumoto, K. Sakamoto, K. Haginoya, K. Iinuma

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Serial MRI findings are described in two patients with Reye's syndrome, demonstrating diffuse cortical and white matter changes. In the acute stage, T2-weighted images showed subtle but definite laminar high signal and contrast-enhanced T1-weighted images laminar enhancement, along the entire cerebral cortex bilaterally. In the chronic stage, unenhanced T1-weighted images showed diffuse cortical laminar high signal. These characteristic MRI features seemed very similar to those of laminar cortical necrosis in hypoxic brain damage. MRI also displayed delayed white matter changes with cerebral atrophy.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
Issue number3
Publication statusPublished - 1996 Apr
Externally publishedYes


  • Cortical laminar necrosis
  • Magnetic resonance imaging
  • Reye's syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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