Review paper: Behavior of ceramic biomaterials derived from tricalcium phosphate in physiological condition

Masanobu Kamitakahara, Chikara Ohtsuki, Toshiki Miyazaki

Research output: Contribution to journalReview article

170 Citations (Scopus)

Abstract

Various calcium phosphates are used for bone repair. Although hydroxyapatite (HA) sintered ceramics are widely used due to their osteoconductivity, its bioresorbability is so low that HA remains in the body for a long time after implantation. In contrast, tricalcium phosphate (TCP) ceramics show resorbable characters during bone regeneration, and can be completely substituted for the bone tissue after stimulation of bone formation. Therefore, much attention is paid to TCP ceramics for scaffold materials for supporting bone regeneration. This paper reviews bioresorbable properties of calcium phosphate ceramics derived from β-TCP and α-TCP.

Original languageEnglish
Pages (from-to)197-212
Number of pages16
JournalJournal of Biomaterials Applications
Volume23
Issue number3
DOIs
Publication statusPublished - 2008 Nov 10

Keywords

  • Bone
  • Calcium phosphate
  • Hydroxyapatite
  • Scaffold
  • Tricalcium phosphate

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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