Retention of words in long-term memory: A functional neuroanatomical study with PET

Jiro Okuda, Toshikatsu Fujii, Atsushi Yamadori, Ryuta Kawashima, Takashi Tsukiura, Hiroya Ohtake, Reiko Fukatsu, Kyoko Suzuki, Masatoshi Itoh, Hiroshi Fukuda

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

We used PET to identify brain regions associated with retention of verbal materials in long-term memory. During a PET scan, subjects repeated many sets of words one after another. In a retention condition, they were simultaneously required to retain 10 key words that were irrelevant to the repetition tasks. Significant increases in regional cerebral blood flow during the retention condition were found in bilateral parahippocampal regions, the left prefrontal and parietal association cortices, the supplementary motor area, the neostriatum and the cerebellum. We clearly demonstrated that retention of verbal materials was accompanied by neural activities in the medial temporal lobes. We also showed that, in the early phase, retention of words in long-term memory recruited left cortical areas surrounding those relevant to verbal short-term memory. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalNeuroReport
Volume11
Issue number2
DOIs
Publication statusPublished - 2000

Keywords

  • Long-term memory
  • Neostriatum
  • Parahippocampal region
  • Parietal association cortex
  • Positron emission tomography
  • Prefrontal cortex
  • Rehearsal
  • Retention
  • Supplementary motor area
  • Verbal short-term memory

ASJC Scopus subject areas

  • Neuroscience(all)

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