Risoluzione di infiltrati polmonari migranti in un paziente con infezione da Mycoplasma pneumoniae e Bordetella pertussis a seguito di terapia con moxifloxacina

Translated title of the contribution: Resolution of migratory pulmonary infiltrates by moxifloxacin in a patient with dual infection of Mycoplasma pneumoniae and Bordetella pertussis

Itsuro Kazama, Tsutomu Tamada, Toshiyuki Nakajima

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

A 37-year-old Japanese woman, who was not vaccinated against Bordetella pertussis, developed a nocturnal fever with persistent dry cough for more than 2 weeks. A chest radiograph showed poorlydefined nodular opacities in the left lung. Due to the significant rise in serum antibodies for both Mycoplasma pneumoniae and B. pertussis, a diagnosis of dual infection with the organisms was made. Despite the use of susceptible antibiotics, the patient's symptoms did not improve and her chest radiograph showed migratory pulmonary infiltrates. However, a quinolone derivative, moxifloxacin, dramatically improved her symptoms and resolved the pulmonary infiltrates shortly after administration. In this case, due to the lymphocyte- stimulatory nature of M. pneumoniae and B. pertussis, an increased immunological response was likely to be involved in the pathogenesis of pneumonia. The immunomodulatory property of moxifloxacin was thought to repress the increased lymphocyte activity, and thus facilitated complete remission of the disease.

Translated title of the contributionResolution of migratory pulmonary infiltrates by moxifloxacin in a patient with dual infection of Mycoplasma pneumoniae and Bordetella pertussis
Original languageItalian
Pages (from-to)288-292
Number of pages5
JournalInfezioni in Medicina
Volume20
Issue number4
Publication statusPublished - 2012 Dec

Keywords

  • Bordetella pertussis
  • Dual infection
  • Immunomodulation
  • Migratory pulmonary infiltrates
  • Moxifloxacin
  • Mycoplasma pneumonia

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Resolution of migratory pulmonary infiltrates by moxifloxacin in a patient with dual infection of Mycoplasma pneumoniae and Bordetella pertussis'. Together they form a unique fingerprint.

Cite this