Reproduction of pressure field in ultrasonic-measurement-integrated simulation of blood flow

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Ultrasonic-measurement-integrated (UMI) simulation of blood flow is used to analyze the velocity and pressure fields by applying feedback signals of artificial body forces based on differences of Doppler velocities between ultrasonic measurement and numerical simulation. Previous studies have revealed that UMI simulation accurately reproduces the velocity field of a target blood flow, but that the reproducibility of the pressure field is not necessarily satisfactory. In the present study, the reproduction of the pressure field by UMI simulation was investigated. The effect of feedback on the pressure field was first examined by theoretical analysis, and a pressure compensation method was devised. When the divergence of the feedback force vector was not zero, it influenced the pressure field in the UMI simulation while improving the computational accuracy of the velocity field. Hence, the correct pressure was estimated by adding pressure compensation to remove the deteriorating effect of the feedback. A numerical experiment was conducted dealing with the reproduction of a synthetic three-dimensional steady flow in a thoracic aneurysm to validate results of the theoretical analysis and the proposed pressure compensation method. The ability of the UMI simulation to reproduce the pressure field deteriorated with a large feedback gain. However, by properly compensating the effects of the feedback signals on the pressure, the error in the pressure field was reduced, exhibiting improvement of the computational accuracy. It is thus concluded that the UMI simulation with pressure compensation allows for the reproduction of both velocity and pressure fields of blood flow.

Original languageEnglish
Pages (from-to)726-740
Number of pages15
JournalInternational Journal for Numerical Methods in Biomedical Engineering
Volume29
Issue number7
DOIs
Publication statusPublished - 2013 Jul 1

Keywords

  • Bio-fluid mechanics
  • Color Doppler imaging
  • Computational fluid dynamics
  • Measurement-integrated simulation
  • Ultrasonic measurement

ASJC Scopus subject areas

  • Software
  • Biomedical Engineering
  • Modelling and Simulation
  • Molecular Biology
  • Computational Theory and Mathematics
  • Applied Mathematics

Fingerprint Dive into the research topics of 'Reproduction of pressure field in ultrasonic-measurement-integrated simulation of blood flow'. Together they form a unique fingerprint.

  • Cite this