Renin release from microdissected superficial, midcortical, and juxtamedullary afferent arterioles in rabbits

Noboru Nushiro, Keishi Abe, Sadayoshi Ito, Seiichi Misawa

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Abstract

In result, we got the following conclusions. 1. Basal renin release per afferent arteriole decreases steeply from superficial to midcortical to juxtamedullary afferent arterioles during both normal and low sodium intake. 2. Isoproterenol (1. 6 X 10-4M) significantly stimulates renin release from all three types of arterioles on either diet; however, only in the superficial arterioles is the increase (?) greater with dietary sodium restriction. These findings indicate substantial heterogeneity of basal and isoproterenol-stimulated renin release, and response to chronic sodium depletion.

Original languageEnglish
Pages (from-to)1113-1116
Number of pages4
JournalThe Japanese Journal Of Nephrology
Volume34
Issue number10
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Nephrology

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