Renal vein plasma renin activity in patients with unilateral renovascular hypertension

Ko Sato, Masahide Seino, Keishi Abe, Minoru Yasujima, Yutaka Imai, Makito Sato, Masao Hiwatari, Ken Omata, Masaya Tanno, Masahiro Kohzuki, Kaoru Yoshinaga

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Plasma renin activity in the renal veins (V) or infrarenal inferior vena cavae (IVC) of 20 patients with unilateral renovascular hypertension (RVH) was measured to determine how renal vein renin ratio (RVRR) compares with renin index (V-IVC/IVC) as a predictor of curability of RVH. Although there was no significant difference between them in predicting curability, 3 out of 4 patients with hypersecretion of renin (V-IVC/IVC ≥0.48) in the stenosed side with contralateral suppression (V-IVC/IVC ≤ 0) on the normal side were cured. In addition, 7 out of 11 patients with contralateral suppression irrespective of values of renin index in the stenosed side were also cured. On the other hand, only one out of 6 patients who had neither hypersecretion nor contralateral suppression was cured. These results reconfirm that significant renin secretion with or without contralateral suppression, or only contralateral suppression of renin is highly suggestive of curable RVH.

Original languageEnglish
Pages (from-to)431-436
Number of pages6
JournalJAPANESE CIRCULATION JOURNAL
Volume52
Issue number5
DOIs
Publication statusPublished - 1988

Keywords

  • Essential hypertension
  • Renal vein renin
  • Renovascular hypertension

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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